| 青心酮的抗氧化作用 |
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| 引用本文： | 冯立明,潘华珍,张之南.青心酮的抗氧化作用[J].药学学报,1987,22(4):241-244. |
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| 作者姓名： | 冯立明 潘华珍 张之南 |
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| 作者单位： | 中国协和医科大学 北京
(冯立明，潘华珍)，中国协和医科大学 北京(张之南) |
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| 摘 要： | 本文以活性氧对红细胞的氧化作用,探讨青心酮的抗氧化作用。体外实验表明,青心酮有抗超氧化物阴离子自由基及羟基自由基对Hb的氧化作用;减少羟基自由基及过氧化氢引起红细胞溶血和脂质过氧化反应。并发现青心酮有清除超氧化物阴离子自由基及羟基自由基的功能,阻止活性氧对红细胞氧化。
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| 关 键 词： | 青心酮 活性氧 脂质过氧化 溶血 |
| 收稿时间： | 1986-07-14 |
THE ANTIOXIDANT ACTION OF 3, 4-DIHYDROXYACETOPHENONE |
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| FENG LI-Ming,PAN Hua-Zhen and ZHANG Zhi-Nan.THE ANTIOXIDANT ACTION OF 3, 4-DIHYDROXYACETOPHENONE[J].Acta Pharmaceutica Sinica,1987,22(4):241-244. |
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| Authors: | FENG LI-Ming PAN Hua-Zhen and ZHANG Zhi-Nan |
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| Abstract: | The effect of 3,4-dihydroxyddacetophenone on hemolysis of erythrocytes induced by active oxygen radicals is presented. When erythrocytes were exposed to active oxygen generated in vitro, hemoglobin was broken down, lipids were peroxidated and hemolysis occured. These reactions were inhibited by 3,4-dihydroxyacetophenone. The results showed that 3,4-dihydroxyacetophenone might act as a scavenger of superoxide and hydroxy radical and might be used as an antioxidant. |
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| Keywords: | 3 4-Dihydroxyacetophenone Active oxygen Lipid peroxidation Hemolysis |
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