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微痕量元素与广西原发性肝细胞癌发病关系的研究
引用本文:吴继周,叶馥荪,莫志纯,黄桂宽,林文业,何聿忠,黄丽娟.微痕量元素与广西原发性肝细胞癌发病关系的研究[J].广西医科大学学报,1988(2).
作者姓名:吴继周  叶馥荪  莫志纯  黄桂宽  林文业  何聿忠  黄丽娟
作者单位:广西医学院,广西医学院,广西医学院,广西医学院,广西测试中心,广西测试中心,广西测试中心
摘    要:本文应用新的微痕量元素检测技术和统计学分析方法——条件Logistic回归模型,探讨微痕量元素Se、Zn、Cu、Fe、Mn、Mo及其比值与广西原发性肝细胞癌发病的关系.研究结果提示:Se是抗癌因子,而Cu、Fe、Zn、Mo是致癌因子,Mn作用不明显.在所研究的17个变量中,以Se/Cu、Cu/Mo、Se/Zn及Fe与广西原发性肝细胞癌发病关系最为密切.

关 键 词:微痕量元素  原发性肝细胞癌  条件Logistic回归模型

A Study of The Relation Between Trace Elements And Primary Hepatocellular Carcinoma in Guangxi, China
Li Houwen,Yang Yongjin.A Study of The Relation Between Trace Elements And Primary Hepatocellular Carcinoma in Guangxi, China[J].Journal of Guangxi Medical University,1988(2).
Authors:Li Houwen  Yang Yongjin
Institution:Li Houwen;Yang Yongjin
Abstract:The relation between trace elements, Se, Zn, Cu, Fe, Mn, Mo and their ratio in human hair and the development of primary hepatocellular carcinoma in Guangxi, China was investigated by case-control study using newer technology in the determination of trace elements and applying multiple condition logistic regression model statistical method.The results of this study suggest that Se is a cause inhibiting factor whereas Cu, Fe, Zn, Mo are cause inducing factors, Mn is found to be of no significance.Among the 17 variables, the closest relationship between the variables and hepatocellular carcinoma in Guangxi, China, appears to be the ratio between Se and Cu (Se/Cu),Cu and Mo (Cu/Mo) , Se and Zn (Se/Zn) as well as Fe.Some differences exist between our work and others previously reported in China, Further study on this problem is indicated.
Keywords:Trace Element  Primary Hepatocellular Carcinoma  Multiple Condition Logistic Regression Model  
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