桥本甲状腺炎的临床病理分析

［ 目的］ 探讨桥本甲状腺炎的临床病理特点．［ 方法］ 对３４ 例住院手术的桥本甲状腺炎病例进行了临床、病理分析．［ 结果］ 病理观察结果表明，甲状腺滤泡萎缩、消失，大量淋巴细胞浸润，核异型性是诊断桥本甲状腺炎的主要病理变化，其次是淋巴滤泡形成、间质纤维组织增生和滤泡上皮嗜酸性变．［ 结论］ 凡成年女性甲状腺肿大，质较硬，无特殊临床表现时应考虑桥本甲状腺炎，需进一步检查，疑为癌时采用术中快速冷冻病理检查，以明确诊断．

Clinicopathological analysis of Hashimoto's thyroiditis

OBJECTIVE To explore the clinicopathological characteristic in Hashimoto's thyroiditis.METHODS The clinical data and pathological specimens of 34 Hashimoto's thyroiditis cases were analysed.RESULTS Histopathological examination reveals that follicular atrophied and disappeared.A large of lymphocytes infiltrated. Nuclear atypia are the most important pathological changes in the diagnosis of Hashimoto's thyroiditis,and the second one are lymphoid follicle formation,stroma fibrosis and acidophilic degeneration of follicular epithelium.CONCLUSION Any enlargement of thyrod cases in adult females with no any special clinical manifestations should be considered as Hashimoto's thyroiditis and need to futher examinations.In suspicious carcinoma cases ,frozen section is necessary in operation.