针刺治疗对注意缺陷多动障碍患儿事件相关电位P3的影响

为观察针刺治疗对注意缺陷多功障碍（ADHD）患儿事件相关电位马的影响,通过对40名患儿和20名正常儿童的事件相关电位P3检测,发现在两种注意状态（主动注意、被动注意）下,ADHD患儿P3出现率为68．9％、46．6％,正常儿童为94．3％、35．7％（P＜0．001）,提示患儿被动注意强而主动注意较弱。ADHD3亚型间P3出现率亦有差异（P＜0．05）。在两种注意状态下,和正常儿童比较ADHD患儿P3潜伏期较长而波幅较低（P＜0．001）。经3个月针刺治疗后P3潜伏期显著缩短,波幅显著提高（P＜0．001）,提示针刺治疗可以促进发育迟缓的患儿大脑神经纤维生长和发育,增加大脑皮层突触数量和质量,从而使可供动员的信息加工的有效资源增加,提高注意水平,特别是主动注意水平;增加了能激活的神经元数量,从而在反映大脑皮层对新型的、重要的与可引起兴趣的感觉输入信息的认识过程指标P3上反映出来。

Effects of Acupuncture on Event Related Potential P3 in Children with Attention Deficit Hyperactivity Disorder

To observe the effects of acupuncture on event related potential P3(P3) in children with attention deficit hyperactivity disorder (ADHD), P3 in 40 ADHD children and 20 normal children was detected.It was founded that the occurrence rate of P3 in ADHD chilthen under the situations of active retention and passive attenhon was 68.9% and 46.6%,and 94.3% and 35.7% in normal children respefavely(P<0.001).This indicated that the passive attention was strengthended and the active attention was weakened in ADHD children. Meanwhile, there were differences among the occurrence ratesin the three subgroups of ADHD (P < 0 .05 ). Under the two attention situations,the incubation periodof P3 was longer and the wave amplitude was lower in ADHD children as comped with the norml children(P<0.001).After the treatment of acupunctme for 3 months,the incubation Pened of P3 wasshortened and the wave amplitude was increased markedly(P<0.001).It is suggested that arupuncture can improve the growth and development of cerebral nerve fibers and increase the number and qualityof synapse in cereblal cortex and improve the attention situations especially the active attention in ADHDchildren.