首页 | 本学科首页   官方微博 | 高级检索  
     

诱发性胸腺淋巴瘤动物模型的建立
引用本文:王洪艳,徐彩云,宋祥福,龚守良. 诱发性胸腺淋巴瘤动物模型的建立[J]. 实验动物与比较医学, 2011, 31(6): 478-482. DOI: 10.3969/j.issn.1674-5817.2011.06.019
作者姓名:王洪艳  徐彩云  宋祥福  龚守良
作者单位:1. 吉林大学公共卫生学院卫生部放射生物学重点实验室,长春130021;北华大学公共卫生学院,长春132001
2. 吉林大学白求恩医学院动物实验中心,长春,130021
3. 吉林大学公共卫生学院卫生部放射生物学重点实验室,长春,130021
摘    要:
胸腺瘤是最常见的纵隔肿瘤,其病因学和发病机制尚不清楚.合适的动物模型是研究该病病因学、发病机制以及治疗措施重要手段.本文就物理、化学和生物因素等致癌因素诱发胸腺瘤肿瘤模型作一回顾,并对其诱发机制以及影响因素作一概述.同时对诱发胸腺瘤模型的优点进行简单综述.

关 键 词:胸腺瘤  化学因素  EBV  电离辐射  动物模型

Establishment of Induced Animal Model with Thymic Lymphoma
WANG Hong-yan,SONG Xiang-fu,CHEN Yu-bing,GONG Shou-liang. Establishment of Induced Animal Model with Thymic Lymphoma[J]. Laboratory Animal and Comparative Medicine, 2011, 31(6): 478-482. DOI: 10.3969/j.issn.1674-5817.2011.06.019
Authors:WANG Hong-yan  SONG Xiang-fu  CHEN Yu-bing  GONG Shou-liang
Affiliation:1. School of Public Health, Beihua University, Jilin 132001, China; 2. Key Laboratory of Radiobiology, Ministry of Health, School of Public Health, Jilin University, Changchun 130021, China; 3. The Second Hospital, Jilin University, Changchun 130021, China)
Abstract:
Thymoma is the most common mediastinal tumor, its etiology and pathogenesis is unclear. It is an invasive important means to establish suitable animal model for studing its etiology, pathogenesis and treatment. In this paper, we review some thymoma tumor model induced by carcinogens such as physical, chemical and biological factors. At the same time their trigger mechanism and influenced factors were also reviewed Then we simply introduce the advantages of the induced thymoma model.
Keywords:Thymoma  Chemical factors  EBV  Ionizing radiation  Animal models
本文献已被 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号