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肿瘤分子靶向治疗药物的应用进展
引用本文:詹琼. 肿瘤分子靶向治疗药物的应用进展[J]. 上海医药, 2011, 32(12): 577-581
作者姓名:詹琼
作者单位:复旦大学附属华山医院肿瘤科,上海,200040
摘    要:
分子靶向治疗作为肿瘤治疗的新手段,正以其低毒、副反应和高治疗效果成为肿瘤治疗研究的热点.按作用靶点以及药物的性质,分子靶向药物可分为数类,主要包括以EGFR为靶点的药物、作用于HER2/erbB2的单克隆抗体、靶向VEGF/VEGFR的药物、以白细胞CD为靶点的单克隆抗体以及作用于多个靶点的药物.本文综述肿瘤分子靶向治...

关 键 词:肿瘤  分子靶向治疗  药物

Progress in the application of molecular targeted drugs for cancer therapy
ZHAN Qiong. Progress in the application of molecular targeted drugs for cancer therapy[J]. Shanghai Medical & Pharmaceutical Journal, 2011, 32(12): 577-581
Authors:ZHAN Qiong
Affiliation:ZHAN Qiong(Department of Oncology,Huashan Hospital,Fudan University,Shanghai,200040)
Abstract:
Molecular targeted therapy is a newly developed approach for cancer therapy.With the advantages of lower toxicity,tolerable side effects and higher performance,molecular targeted therapeutic drugs(MTTD)have become a critical focus in cancer research.According to the targets and the nature of these drugs,MTTD were divided into several classes,including the drugs targeting EGFR,the monoclonal antibodies to HER2/erbB2,the drugs targeting VEGF/VEGFR,the monoclonal antibodies to CD antigen in white cells,and mul...
Keywords:cancer  molecular targeted therapy  drugs  
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