聚焦超声治疗外阴硬化性苔藓的疗效观察

目的探讨聚焦超声治疗外阴硬化性苔藓的疗效。方法2005年7月～2005年12月用聚焦超声治疗外阴硬化性苔藓病人30例(超声组),同期采用皮质激素、雄激素等药物治疗外阴硬化性苔藓病人33例(对照组),对两组病人的疗效进行比较分析。结果超声组与对照组在治疗后瘙痒评分有显著性差异(P<0.05),病灶面积缩小比较亦有显著性差异(P<0.01)。超声组和对照组的复发率分别为6.25%和50%。结论聚焦超声是一种安全、无创、疗效好、操作简便的治疗外阴硬化性苔藓的方法。

Treatment of Lichen Sclerosus of Vulva with High-intensity Focused Ultrasound

Objective To observe the effectiveness of high-intensity focused ultrasound(HIFU)in the treatment of lichen sclerosus of vulva.Methods 63 patients with lichen sclerosus of vulva between July 2005 to December 2005 were divided into two groups at random,ultrasound group and control group.Patients in ultrasound group were treated with HIFU.Those in control group were treated with hormone.Results The scores of itch had difference after treatment in both group(P<0.05).The decrease of lesion area in both group had significant difference after treatment(P<0.01).The recrudescence was 6.25% and 50%.Conclusions HIFU is an effective,safe and no-scaring technique in treatment of lichen sclerosus of vulva.