| 角膜新生血管中细胞与分子的研究进展 |
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| 引用本文： | 高月兰,潘玉苗,杨燕宁.角膜新生血管中细胞与分子的研究进展[J].国际眼科杂志,2021,21(11):1875-1880. |
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| 作者姓名： | 高月兰 潘玉苗 杨燕宁 |
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| 作者单位： | 中国湖北省武汉市,武汉大学人民医院眼科中心,中国湖北省武汉市,武汉大学人民医院眼科中心,中国湖北省武汉市,武汉大学人民医院眼科中心 |
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| 基金项目： | 国家自然科学基金资助项目(No.81770899) |
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| 摘 要： | 多种眼部损伤可诱导角膜新生血管形成，促进疾病发展，造成角膜水肿、视力受损，甚至失明，因此抑制角膜新生血管有助于延缓疾病进程并降低角膜损伤，具有十分重要的临床意义。本文将对参与角膜新生血管形成的细胞及分子作最新的系统论述，并分析可能的抑制靶点，以期为科研及临床提供参考。
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| 关 键 词： | 角膜新生血管 细胞 血管因子 RNA 细胞外基质 |
| 收稿时间： | 2021/2/20 0:00:00 |
| 修稿时间： | 2021/9/18 0:00:00 |
Research progress of cells and molecules in corneal neovascularization |
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| Yue-Lan Gao,Yu-Miao Pan and Yan-Ning Yang.Research progress of cells and molecules in corneal neovascularization[J].International Journal of Ophthalmology,2021,21(11):1875-1880. |
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| Authors: | Yue-Lan Gao Yu-Miao Pan and Yan-Ning Yang |
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| Institution: | Eye Center, Renmin Hospital of Wuhan University, Wuhan 430061, Hubei Province, China,Eye Center, Renmin Hospital of Wuhan University, Wuhan 430061, Hubei Province, China and Eye Center, Renmin Hospital of Wuhan University, Wuhan 430061, Hubei Province, China |
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| Abstract: | Various ocular injuries can induce corneal neovascularization, which promote the development of diseases, causing corneal edema, impaired vision and even blindness. Therefore, with very important clinical significance, inhibiting corneal neovascularization can help to delay the progression of diseases and reduce corneal damage. This article will make the latest systematic discussion on the cells and molecules involved in corneal neovascularization, and analyze the possible inhibitory targets, hoping to provide references for scientific research and clinical practice. |
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| Keywords: | corneal neovascularization cell vascular factor RNA extracellular matrix |
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