武汉地区32家医院2009-2011年抗病毒药利用分析

目的:了解武汉地区医院抗病毒药的利用情况及趋势。方法:采用回顾性方法,对武汉地区32家医院2009-2011年抗病毒药的销售金额、用药频度(DDDs)和日均费用(DDC)等进行统计、分析。结果:3年来该地区医院抗病毒药总销售金额呈逐年上升趋势,居前5位的均为核苷类药,约占总销售额的90%;阿德福韦酯、替比夫定的DDDs较高,一直居前2位;缬更昔洛韦的DDC值最高(达5475元/日),金刚烷胺的DDC最低(约0.13元/日),其次是三氮唑核苷(约3元/日)。结论:该地区医院临床应用抗病毒药品种相对单一,主要为核苷类抗病毒药;抗病毒药基本用于病毒性肝炎的治疗,用于艾滋病治疗的药品较少。

Analysis of the Utilization of Antiviral Drugs in 32 Hospitals from Wuhan Area during the Period of 2009-- 2011

OBJECTIVE： To investigate the utilization and trends of antiviral drugs in hospitals of Wuhan area. METHODS： Using a retrospective method, the utilization of antiviral drugs in 32 hospitals from Wuhan area during 2009--2011 was analyzed statistically in respect of consumption sum, DDDs and DDC. RESULTS： The consumption sum of antiviral drugs was increasing year by year during 2009--2011. Top 5 drugs were nucleoside antiviral drugs, accounting for about 90% of total consumption sum. The DDDs of adefovir dipivoxil and telbivudine took up top places in the list of DDDs. The DDC of valganciclovir was the highest （5 475 yuan per day） and amantadine was the lowest （about 0.13 yuan per day）, followed by ribavirin （about 3 yuan per day）. CONCLUSION： The kinds of antiviral drugs are relatively single in hospitals from Wuhan area, and they are mainly nucleotide an- tivirus drugs. The antiviral drugs are mostly used for treatment of hepatitis virus, and small amount are used for AIDS. As a result, the R＆D of antiviral drugs still has some room for development in China.