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Immunohistochemical Localization of Estrogen and Progesterone Receptorin Decidua and Villi of Human Early Pregnancy
作者姓名:王介东 伏耀 施文良 朱逢第 乔根梅 王幼劬
作者单位:[1]NationalResearchinstituleforfamilyplanningbeijing100081,people'srepublicofchina [2]NationalResearchinstituleforfamilyplanningbeijing100081,people'srepublicofchina
摘    要:Imtnunohistochemical assessment of estrogen recceptor(ER) and progesterone receptors(PR) were performed using monoetonat antibodies to the receptors. A totalof 81 samples. from pregnant women at 5-13 weeks of gestation were immunostained by peroxidase anti-peroxidase method (PAP). hnmunostaining pattern of PR in early pregnant decidua was similar to that of the late luteal phase of normal endometrium characterized by little reaction in supecfieiat glandular epithelia and retatively intense in stroma. Positive stainig was atsa revealed in structure of blood vessels including pericyte and smooth muscle cells. An interesting finding is that endothelial cells Of the vessels expressed PR which has not been reported in normal cyclic endometrium. The endothelial nature of their PR partitive cell was further confirmed by immunostaining of specific endothelial marker, Factor VⅢ. The trophoblast population in villi anddecidua also showed positive reaction inctnding villous trophoblast, column andinterstitial trophobtast. In eontrast to PR, little ER were revealed in deteected tissue.

关 键 词:免疫组织化学 雌激素 孕酮 早孕
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