单肺通气胸腔镜手术对幼猪血流动力学及血气的影响

目的研究单肺通气麻醉胸腔镜手术对幼猪血流动力学及动脉血气的影响。方法选取健康家猪8只，体重(7.1±0.7)kg。吸入1%异氟醚维持麻醉，颈部气管切开行左主支气管插管。通过Swan-Ganz漂浮导管和动脉导管动态监测血流动力学及动脉血气变化。结果单肺通气后平均肺动脉压（mPAP）从(15.8±1.5)mm Hg(1 mm Hg=0.133 kPa)升至(19.5±2.3) mm Hg(P＜0.05)，血氧饱和度、动脉血气及其它血流动力学指标无明显变化。结论幼猪可以较好地耐受单肺通气麻醉胸腔镜手术。

Effects of one lung ventilation on hemodynamics and blood gas during thoracoscopic surgery in piglets

Objective: To evaluate the effects of one lung ventilation on hemodynamics and blood gas during thoracoscopic surgery in piglets. Methods: Eight domestic pigs weighting (7.1±0.7) kg were included in this study. The anaesthesia was maintained with 1% isoflurance. After tracheotomy, an endotracheal tube was positioned in the left mainstem bronchus. Hemodynamic parameters as well as blood gas analyses were obtained using Swan-Ganz and arterial catheter. Results: During one lung ventilation, pulmonary artery pressure increased from (15.8±1.5) mm?Hg to (19.5±2.3) mm?Hg. Arterial oxygen saturation, blood gas analyses and other hemodynamic parameters remained unchanged. Conclusion: One lung ventilation was well tolerated in regard to hemodynamics and blood gas analyses in piglets.