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Sensitivity of VHL mutant kidney cancers to HIF2 inhibitors does not require an intact p53 pathway
Authors:Laura A. Stransky  Sean M. Vigeant  Bofu Huang  Destiny West  Thomas Denize  Emily Walton  Sabina Signoretti  William G. Kaelin  Jr.
Affiliation:aDepartment of Medical Oncology, Dana–Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215;bDepartment of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115;cHHMI, Chevy Chase, MD, 20815
Abstract:
Keywords:ccRCC   HIF   VHL   TP53   belzutifan
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