睡眠质量及时间与2型糖尿病的关系研究

目的 探讨睡眠质量和睡眠时间与2型糖尿病的关系.方法 于2008年采用多阶段分层随机抽样的方法从徐州市居民健康状况资料中抽取16 893人作为研究对象,对其进行睡眠与2型糖尿病关系的描述性流行病学分析,计数资料组间比较采用x2检验,多因素分析采用Logistic回归模型,并调整混杂因素,计算OR值及95％ CI.结果 研究对象中睡眠质量良好、一般、差3组2型糖尿病新发现率分别为5.39％、6.30％和11.66％.睡眠质量一般、差两组2型糖尿病新发现率同睡眠质量良好组2型糖尿病新发现率相比,差异有统计学意义(x2值分别为4.98和44.90,均有P＜0.05).睡眠时间＜6h、6～8h、＞8h组的2型糖尿病新发现率分别为7.95％、5.69％和6.47％,睡眠时间＜6h组与睡眠时间6～8h组2型糖尿病新发现率的差异有统计学意义(x2=5.28,P＜0.05).调整性别、年龄、文化程度、职业、糖尿病家族史、吸烟、饮酒、非职业性体育活动等混杂因素后,年龄、体质指数、2型糖尿病家族史、睡眠质量差和每天睡眠时间＜6h是2型糖尿病发生的独立危险因素.结论 睡眠质量差和每天睡眠时间＜6h同2型糖尿病的发生有关,是2型糖尿病发生的危险因素.

Association study of sleep quality and duration with type 2 diabetes

Objective To study the association of sleep quality and duration with type 2 diabetes in community population.Methods An investigation of the residents health status of Xuzhou with multi-stage stratified random sampling in 2008 were conducted,from which a total of 16 893 residents aged 18～75 years were selected by cluster sampling method,and investigated by a standard questionnaire on risk of diabetes,sleep quality and sleep duration,comparison of the new discovery rate of diabetes in different group was conducted by chi square test.The association of factors with diabetes was evaluated by Logistic regression analysis.Results The new discovery rate of diabetes in the poor,common and well sleep quality groups were 11.66%,6.30% and 5.39% respectively,there were significant differences among poor and common sleep quality and well sleep quality.The new discovery rate of diabetes in the sleep time 6 h,6～8 h and 8 h groups were 7.95%,5.69% and 6.47% respectively,there was a significant difference between shorter sleep duration（6 h） and general sleep duration（6～8 h）.After adjusting for gender,age,educational level,occupation,family history of diabetes,smoking and other confounding factors,compared with individuals sleeping 6～8 h and well sleep quality habitually,individuals sleeping 6 h or poor sleep quality had adjusted ORs for diabetes of 1.84（95% CI：1.39～2.44） and 1.43（95% CI：1.15～1.77）,respectively.Conclusions The poor quality of sleep and sleep duration 6 h per night were the independent risk factors of type 2 diabetes.