从业人群乙型肝炎病毒标志物的检测分析

目的 了解从业人群HBV感染的现状,进一步加强对HBsAg携带者的管理.方法 采用ELISA法,对太原铁路地区从业人群进行HBsAg、HBeAg和抗-HBc IgM检测.结果 2000年1月-2006年8月共检测41 164人,其中HBsAg阳性者588人,阳性率1.43%.在588名HBsAg阳性者中,HBeAg阳性者40人,阳性率6.80%,其阳性率随年龄递增而下降(x2=30.13,P＜0.01);抗-HBc IgM阳性者6人,阳性率1.02%,各年龄组间抗-HBc IgM的阳性率差异无统计学意义(x2=1.61,P＞0.05).在HBV血清标志物组合模式中,以HBsAg阳性+HBeAg阴性+抗-HBc IgM阴性所占比例最高,占92.52%,以HBsAg阳性+HBeAg阳性+抗-HBc IgM阳性所占比例最低,占0.34%.结论 太原铁路地区从业人群属于HBV低流行人群,结果显示加强对HBsAg携带者的管理是关键.

Analysis of detection on hepatitis B virus serum marks in the occupational population

Objective To acknowledge the status of HBV infection in the occupational population in Taiyuan and deal with HBsAg carrier effectively.Method Sera HBsAg,HBeAg and anti-HBe IgM of the occupational population were detected by ELISA.Results 41 164 persons were detected from January 2000 to August 2006,HBsAg of 588 persons was positive(1.43%).Among the 588 HBsAg positive persons,40 were HBeAg positive(6.80%),HBeAg positive rate decreased while age increased(x2=30.13,P＜0.01);6 were anti-HBc IgM positive(1.02%),there were no statistical difference in different age groups(x2=1.61,P＞0.05).Among the 588 HBsAg positive persons,the people of HBsAg positive,HBeAg negative,anti-HBc IgM negative were 92.52%,those of HBsAg positive,HBeAg positive,anti-HBc IgM positive were 0.34%.Conclusions The positive rate of HBV infection in the railway occupational population in Taiyuan is low,and the result shows that it is important for the HBsAg carrier management.