不透X线标志物法检测胆汁反流性胃炎患者的胃排空障碍

目的采用不透X线标志物法(ROMs)检测胃固体排空功能,探讨胃固体排空障碍在胆汁反流性胃炎(bile refluxgastritis,BRG)中的存在和作用。方法研究对象共80例,包括正常对照(health control,HC)27例;原发性胆汁反流性胃炎(primary bile reflux gastritis,PBRG)组32例;继发性胆汁反流性胃炎(secondary bile reflux gastritis,SBRG)21例。受试者食用等量试餐时同时口服装有20粒钡条的胶囊,餐后120 min及240 min行消化道透视检查并摄片。计算120 min及240 min胃排空率。结果PBRG组与HC组及SBRG组比较,120 min及240 min胃排空率均有明显延迟(P<0.05),SBGR组与HC比较,4h胃排空率有所延迟,但差异无统计学意义(P>0.05)。结论PBRG组存在明显的胃排空功能障碍,SBRG组无明显胃排空功能障碍。

Disturbance of Gastric Emptying in Bile Reflux Gastritis: with Radio-opaque Markers

Objective To detect the delay of gastric emptying in bile reflux gastritis with radio-opaque markers.Methods 80 cases were divided into 3 groups,27 cases as healthy control(HC);32 patients with primary bile reflux gastritis(PBRG),and 21 with secondary bile reflux gastritis(SBRG).All the cases took the same amount of test meal which contained a capsule with 20 barium sulfate pieces.Gastrointestinal fluoroscopy was performed after meals 120 and 240 min respectively.Then the rate of gastric emptying was measured.Results There was significant delay in gastric emptying of solids for PBRG patients compared with HC and SBRG patients(P<0.05).Compared with HC cases,the gastric emptying of solids for SBRG patients showed somewhat delay but there was no statistically significant difference between them(P>0.05).Conclusion PBRG patients show significant gastric emptying disturbance with radio-opaque markers.SBRG patients do not show significant delay of gastric emptying.