心率变异性新指标对左室功能的评定价值

目的在已知有心脏疾病并伴有左室收缩功能降低的患者中，评定心率变异性（HRV）频域分析新指标。方法病变组：66例左室收缩功能降低者；对照组：64例心脏结构功能正常且无严重冠脉狭窄者。用5min心电图测定心率变异性频域中极高频成分并生成新指标VHF指数（VHFI）。结果病变组VHFI显著高于对照组（19．17±13．35vs11．37±10．77，p〈0．05）；VHFI与左室收缩功能呈负相关（R=-0．612）；以VHFI〉15为阳性，VHFI〈15为阴性，对于左室收缩功能降低的预测敏感性和特异性分别为57．58％和78．13％。结论VHFI可以作为有价值的指标，用于急诊快速评定左室功能。

A novel heart rate variability Index for evaluation of left ventricular function

Objective We studied a new index based on frequency-domain analysis of Heart Rate Variability （HRV） and tested that on patients with known cardiac diseases and reduced left ventricular systolic function. Methods We divided patients （n = 130） to study group （n = 66） consisting of patients with decreased left ventricular systolic fimction, and control group （n = 64） consisting of patients with normal heart structure and function and without severe coronary ＇artery stenosis （〈50%）. We calculated Very High Frequency （VHF） component based on five-minute ECG recordings and used a new VHF Index （VHFI）. Results VHFI in study group was significant high than that in control group （19.17 ± 13.35 vs 11.37 ± 10.77 ）. VHFI had correlation with ventricular systolic function （R=-0.612）. We defined the positive test as VHFI〉15 and negative test as VHFI〈15 and obtained sensitivity of 57.58% and specificity of 78.13% for predicting decreased left ventricular systolic function. Conclusion We found out that VHFI has potential to be a useful tool for quick evaluation of left ventricular function in emergency setting.