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功能性消化不良286例临床分析
引用本文:张海利,王斌全,温树信,皇甫辉,柴向斌. 功能性消化不良286例临床分析[J]. 实用口腔医学杂志, 2008, 37(5): 413-414
作者姓名:张海利  王斌全  温树信  皇甫辉  柴向斌
作者单位:山西医科大学第一医院 (030001)
摘    要:
功能性消化不良(FD)占消化科门诊患者的50%左右。本文回顾分析了我院消化科2004-2005年诊治的286例FD临床资料,现报告如下。

关 键 词:功能性消化不良  临床分析  门诊患者  临床资料  消化科
修稿时间:2008-01-16

Study on expression of eukaryotic initiation factor-4E in laryngeal squamoes cell carcinoma
ZHANG Hai-li,WANG Bin-quan,WEN Shu-xin,HUANGFU Hui,CHAI Xiang-bin. Study on expression of eukaryotic initiation factor-4E in laryngeal squamoes cell carcinoma[J]. Journal of Practical Stomatology, 2008, 37(5): 413-414
Authors:ZHANG Hai-li  WANG Bin-quan  WEN Shu-xin  HUANGFU Hui  CHAI Xiang-bin
Abstract:
Objective The expression of eIF4E was studied by detecting their expression in laryngeal squamous cell carcinoma(LSCC).Methods An immunohistochemical analysis with antibody to eIF4E was performed on 52 specimens of the LSCC,20 specimens of dysplasia,30 specimens of hyperplasia and 10 specimens of normal mucosa;Western-blot analysis was performed on tumor core,transition core and "tumor-free" core of 20 specimens of fresh LSCC using anti-eIF4E antiserum.Results All 52 patients(100%)of the LSCC overexpressed eIF4E.It was remarkably higher than that in the control group.The expression of eIF4E protein level from "tumor-free" core,transition core and tumor core of LSCC appeared progressive overexpression.Conclusion Overexpression of eIF4E may be a molecular marker of malignant transformation and progression in LSCC.
Keywords:Eukaryotic initiation factor-4E  Immunohistochemistry  Blotting far-Western  Laryngeal neoplasms
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