白内障超声乳化联合人工晶状体植入术后泪膜功能变化

目的 探讨白内障超声乳化联合人工晶状体植入术对泪膜功能的影响.方法 随机抽取2007年1月至2008年1月行白内障超声乳化联合人工晶状体植入术的患者75例(75眼),术前、术后1 d、1周、2周及1个月行干眼症状评分、角膜荧光素染色、泪膜破裂时间(breaking-up time,BUT)和基础泪液分泌实验(Schier-met test,STT)检查.利用统计学软件SPSS 16.0进行数据分析.结果 与术前相比,术后1 d、1周及2周的BUT明显缩短,干眼症状评分及角膜荧光素染色等级明显增高,差异有统计学意义(P<0.05),而SIT仅在术后1 d差异有统计学意义.术后1个月上述指标恢复至术前水平,与术前比较差异无统计学意义(P>0.05).结论 白内障超声乳化联合人工晶状体植入术后短期内影响患者的泪膜功能,1个月后基本恢复正常.

Clinical study on tear film changes after phacoemulsification combined with intraocular lens implantation

Objective To investigate the tear film changes after phacoemulsification combined with intraocular lens implantation. Methods Seventy-five patients (75 eyes) with cataract who had undergone phacoemulsification com-bined with intraocular lens implantation from Jan 2007 to Jan 2008 were concluded in the study. Subjective scores for dry-hesS,COrneal fluorescein staining,tear break-up time and Schiermer test values were measured preoperatively and 1 day and 7,14,30 days postoperatively. Data were analyzed by SPSS 16.0. Results At 1 day and 7,14 days postoperatively, the mean tear break-up time all reduced greatly, but the grades of subjective score for dryness and corneal fluorescein stai-ning increased significantly (P < 0. 05). From the 7th day, there was no significant difference in the SIT value. At 30 days postoperatively, all indexes recovered to the preoperative levels (P > 0. 05). Conclusions Phacoemulsification combined with intraecular lens implantation might relate to the changes of postoperative tear film stability in a short term, which would recover 1 month later. (Chin J Ophthalmol and Otorhinolaryngol,2009 ,9 :225-227)