拔牙后应用脱细胞真皮基质对保存牙槽嵴的影响

目的：观察脱细胞真皮基质植入拔牙创后牙槽嵴的吸收情况,评价脱细胞真皮基质对于保存牙槽嵴的影响。方法：选用本地产健康成年杂种犬16只,拔除双侧下颌第一前磨牙,左侧拔牙创植入脱细胞真皮基质作为实验组,右侧拔牙创作为空白对照。16只犬随机分为两组,分别于第4、12周处死1组动物。测量第4周、第12周拔牙处的牙槽嵴高度;拔牙创组织制作HE染色切片行组织学观察。结果：第4、12周实验组牙槽嵴高度均明显高于对照组（P〈0.01）;第4周实验组较对照组在组织学上更为成熟。结论：脱细胞真皮基质可以促进拔牙创的早期愈合,保存牙槽嵴高度。

Influence of Embedded Acellular Dermal Matrix on the Preservation of Alveolar after Tooth Extraction

Objective：To observe the absorption of alveolar after acellular dermal matrix was embedded in tooth extraction wound,and to evaluate the influence of acellular dermal matrix on the preservation of alveolar.Methods：16local healthy adult hybrid dogs were chosen,and their first premolars of both mandibulae were extracted.The left side tooth extraction wound was embedded with acellular dermal matrix and regarded as the experimental group,while the right side tooth extraction wound was treated as the control group.16dogs were randomly divided into two groups,and they were executed at the 4th week and 12th week respectively.The alveolar heights of tooth extraction parts were measured at the 4th week and 12th week.Tooth extraction wounds were made into HE stained sections for histological observation.Results：The alveolar height of the experimental group was significantly higher than that of the control group at the 4th week and 12th week（P0.01）,and the experimental group of the 4th week was more mature than the control group histologically.Conclusion：The acellular dermal matrix can promote the early healing of tooth extraction wound and the preservation of alveolar height.