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| 慢性阻塞性肺疾病与急性肺炎患者血小板活化功能对比分析 | |
| 引用本文： | 杨秀竹,杨静,刘洪斌. 慢性阻塞性肺疾病与急性肺炎患者血小板活化功能对比分析[J]. 陕西医学杂志, 2012, 41(1): 98-99 |
| 作者姓名： | 杨秀竹 杨静 刘洪斌 |
| 作者单位： | 天津市南开医院,天津,300100 |
| 摘 要： | 目的:探讨慢性阻塞性肺疾病(COPD)和急性肺炎患者的血小板活化状况进。方法:采用荧光素标记的CD61,CD62p和PAC-1三种单克隆抗体对49例COPD患者和57例急性肺炎患者及20例健康对照组的全血中血小板进行直接免疫荧光染色,然后采用流式细胞仪进行检测。结果:COPD组与急性肺炎组血小板表面受体表达无显著性差异(P>0.05),但两组血小板表面受体表达均明显高于健康对照组(P<0.01)。结论:血小板活化与肺疾病引起的血栓形成有关。 |
| 关 键 词： | 肺疾病,慢性阻塞性/血液 肺炎/血液 血小板活化 对比研究 |
Analysis the platelet activation in patients with chronic obstructive pulmonary disease and acute pneumonia |
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| Yang Xiuzhu , Yang Jing , Liu Hongbin. Analysis the platelet activation in patients with chronic obstructive pulmonary disease and acute pneumonia[J]. Shaanxi Medical Journal, 2012, 41(1): 98-99 | |
| Authors: | Yang Xiuzhu Yang Jing Liu Hongbin |
| Affiliation: | Yang Xiuzhu Yang Jing Liu Hongbin Nankai Hosipital of Tianjin City(Tianjing 300100) |
| Abstract: | Objective:To compare and analysis the platelet activation in patients with chronic obstructive pulmonary disease and acute pneumonia.Methods:Utilize FCM to detect the platelet activators CD61,CD62p,PAC-1,which were marked with fluorescent mono-antibody.Results:The expression of platelet surface receptors of CD62p and PAC-1 in COPD and acute pneumonia was no significant difference,but the expression of platelet surface receptors in these two groups was statistically higher than those in controls(P<0.01).Conclusion:There is a relationship between platelet activation and thrombus cased by pulmonary diseases. |
| Keywords: | Pulmonary disease chronic obstructive/blood Pneumonia/blood Platelet activation Comparative study |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |