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Protection against Yersinia infection induced by non-virulence-plasmid-encoded antigens |
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| Authors: | M Simonet P Berche D Mazigh M Veron |
| Abstract: | Specific immunity against Yersinia was induced by plasmid-encoded antigens not associated with virulence. Mice were immunised with viable bacteria from a virulence-plasmid-cured strain of Y. pseudotuberculosis. This antigenic stimulation generated specific protection against virulence-plasmid-harbouring strains of Y. pseudotuberculosis and Y. pestis, demonstrating that protection can be generated by organisms lacking plasmid-encoded virulence antigens. |
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