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喹硫平与利培酮治疗精神分裂症的对照研究
引用本文:刘红,罗汝琴. 喹硫平与利培酮治疗精神分裂症的对照研究[J]. 中国民康医学, 2011, 23(20): 2483+2494. DOI: 10.3969/j.issn.1672-0369.2011.20.001
作者姓名:刘红  罗汝琴
作者单位:武汉市武昌医院,湖北武汉,430063
摘    要:
目的:探讨喹硫平治疗精神分裂症的疗效及安全性。方法:将40例患者随机分为两组,分别给予喹硫平与利培酮治疗,疗程8周。采用阳性和阴性症状量表(the postitve and negative syndrome scale,PANSS)和副反应量表(treatment emergent symptoms scale,TESS)评定疗效及不良反应。结果:喹硫平与利培酮治疗精神分裂症疗效相当,两组PANSS评分差异无显著性(P>0.05);两组TESS发生率比较,喹硫平组不良反应少(P<0.05)。结论:喹硫平是治疗精神分裂症安全、有效的药物。

关 键 词:喹硫平  利培酮  精神分裂症

A comparative study between Quetiapine and Risperidone in the treatment of schizophrenia
LIU Hong,LUO Ru-qin. A comparative study between Quetiapine and Risperidone in the treatment of schizophrenia[J]. medical journal of chinese peoples health, 2011, 23(20): 2483+2494. DOI: 10.3969/j.issn.1672-0369.2011.20.001
Authors:LIU Hong  LUO Ru-qin
Affiliation:LIU Hong,LUO Ru-qin (Wuchang Hospital,Wuhan 430063,China)
Abstract:
Objective:To explore the efficacy and safety of Quetiapine in the treatment of schizophrenia.Methods:40 schizophrenics were randomly divided into two groups,with Quetiapine or Risperidone for eight weeks.The efficacy and side effects were assessed with PANSS and TESS.Results:No remarkable differences were found in PANSS scores between the two groups,but the side effects of Quetiapine were fewer than that of Risperidone.Conclusion: Quetiapine is an effective and safe drug in the treatment of schizophrenia.
Keywords:Quetiapine  Risperidone  Schizophrenia  
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