| 艾司西酞普兰与氯米帕明治疗抑郁症对照研究 |
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| 引用本文： | 苏宗霞,傅列云,刘蕊. 艾司西酞普兰与氯米帕明治疗抑郁症对照研究[J]. 中国民康医学, 2011, 23(17): 2136-2137. DOI: 10.3969/j.issn.1672-0369.2011.17.016 |
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| 作者姓名： | 苏宗霞 傅列云 刘蕊 |
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| 作者单位： | 淄博市精神卫生中心,山东淄博,255100 |
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| 摘 要： | 目的:评价艾司西酞普兰治疗抑郁症的临床疗效及安全性。方法:用艾司西酞普兰和氯米帕明对66例住院抑郁症患者进行为期6周的随机对照研究。应用HAMD、CGI-SI及TESS量表评估和比较两者的疗效及安全性。结果:治疗6周后,艾司西酞普兰组和氯米帕明组的有效率分别为87.50%和84.38%,两组患者疗效差异无显著性(P>0.05);艾司西酞普兰不良反应明显少于氯米帕明(P<0.01),且耐受性好。结论:艾司西酞普兰治疗抑郁症疗效好,安全性高。
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| 关 键 词： | 艾司西酞普兰 氯米帕明 抑郁症 |
Comparative study of escitalopram and clomipramine in treatment of depression |
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| SU Zong-xia,FU Lie-yun,LIU Rui. Comparative study of escitalopram and clomipramine in treatment of depression[J]. medical journal of chinese peoples health, 2011, 23(17): 2136-2137. DOI: 10.3969/j.issn.1672-0369.2011.17.016 |
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| Authors: | SU Zong-xia FU Lie-yun LIU Rui |
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| Affiliation: | SU Zong-xia,FU Lie-yun,LIU Rui(Zibo Mental Health Center,Shandong 255100) |
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| Abstract: | Objective:To evaluate the efficacy and safety of escitalopram in treatment of depression.Methods:66 inpatients with depression were randomly assigned to receive escitalopram and clomipramine for 6 weeks.All the inpatients were evaluated with HAMD,CGI-SI and TESS.Antidepressive effective was compared between 2 drugs.Results: At 6 weeks,the effective rate of escitalopram group and the clomipramine group were 87.50% and 84.38% respectively,there was no significant difference in clinical efficacy between the tw... |
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| Keywords: | Escitalopram Clomipramine Depression |
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