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诺和龙联合甘精胰岛素治疗48例精神病合并糖尿病的临床观察
引用本文:陈永康,黄俊华,陈红梅. 诺和龙联合甘精胰岛素治疗48例精神病合并糖尿病的临床观察[J]. 中国民康医学, 2011, 23(17): 2144-2146. DOI: 10.3969/j.issn.1672-0369.2011.17.020
作者姓名:陈永康  黄俊华  陈红梅
作者单位:东风公司茅箭医院十堰市精神病院,湖北十堰,442000
摘    要:
目的:探讨诺和龙联合甘精胰岛素在精神病合并糖尿病患者治疗中的疗效。方法:48例精神病合并糖尿病患者随机分为诺和龙与甘精胰岛素组(治疗组)25例,格列吡嗪联合中效鱼精蛋白锌人胰岛素(NPH)组(对照组)23例。依照空腹血糖(FBG)水平调整胰岛素用量,治疗目标值FBG<7.0 mmoL/L,治疗时间12周。观察两组患者治疗前后空腹(FBG)及餐后2 h血糖(2 h PBG)水平、低血糖、糖化血红蛋白(HbAlc)及体质量指数(BMI)等指标的变化情况。结果:两组治疗后FBG、2 h PBG及HbAlc均明显低于治疗前,观察组低血糖发生率明显低于对照组(P<0.05),两组间治疗后血糖无明显差异(P>0.05)。结论:诺和龙与甘精胰岛素可迅速、有效地控制精神病合并糖尿病患者的血糖,低血糖发生率低,具有安全、方便的特点,是精神病合并糖尿病患者控制血糖理想的治疗方案。

关 键 词:精神病  糖尿病  甘精胰岛素  诺和龙(瑞格列奈)

Clinical observation of Repaglinide combined with insulin glargine in treatment of psychiatric patients with diabetes mellitus
CHEN Yong-kang,HUANG Jun-hua,CHEN Hong-mei. Clinical observation of Repaglinide combined with insulin glargine in treatment of psychiatric patients with diabetes mellitus[J]. medical journal of chinese peoples health, 2011, 23(17): 2144-2146. DOI: 10.3969/j.issn.1672-0369.2011.17.020
Authors:CHEN Yong-kang  HUANG Jun-hua  CHEN Hong-mei
Affiliation:CHEN Yong-kang,HUANG Jun-hua,CHEN Hong-mei(Dongfeng Maojian Hospital,Shiyan Psychiatric hospital,Hubei 442000,China)
Abstract:
Objective:To investigate the therapeutic efficacy of Repaglinide combined with insulin glargine in treatment of psychiatric patients with diabetes mellitus.Methods:48 cases of psychiatric patients with diabetes mellitus were randomly divided into two groups: treatment group of Repaglinide combined with insulin glargine(group A,n=25) and treatment group of Glipizide combined with Neutral Protamine Hagedorn(NPH) Insulin(group B,n=23).The insulin dosages of these two groups are adjusted according to the fastin...
Keywords:Mental illness  Diabetes  Insulin glargine  Repaglinide  
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