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慢性乙型肝炎患者血清角蛋白18裂解片段及其应用研究进展
引用本文:曹竹君,刘柯慧,王晖. 慢性乙型肝炎患者血清角蛋白18裂解片段及其应用研究进展[J]. 中华临床感染病杂志, 2014, 0(4): 372-376
作者姓名:曹竹君  刘柯慧  王晖
基金项目:国家自然科学基金(81070334);“十二·五”国家科技重大专项资助项目(2012ZXl005004-002);上海市公共卫生人才培养计划(GWDTR201202);上海市卫生和计划生育委员会重点课题(20134004)
摘    要:
近年来,血清角蛋白18及其裂解片段在肝病诊断方面的应用潜力引起了国内外研究者的强烈兴趣,但其在慢性乙型肝炎方面的应用研究较少。该文总结和探讨了循环血角蛋白18裂解片段M30及M65水平变化在慢性乙型肝炎中的意义以及应用前景。

关 键 词:肝炎  乙型  慢性  凋亡  坏死  角蛋白18

Progress on serum levels of keratin-18 fragments in chronic hepatitis B and perspective of its application
Cao Zhujun,Liu Kehui,Wang Hui. Progress on serum levels of keratin-18 fragments in chronic hepatitis B and perspective of its application[J]. , 2014, 0(4): 372-376
Authors:Cao Zhujun  Liu Kehui  Wang Hui
Affiliation:Cao Zhujun,Liu Kehui,Wang Hui. Department of Infectious Diseases,Shanghai Ruijin Hospital,Shanghai,China Corresponding author : Wang Hui,Email : wanghui
Abstract:
The diagnostic value of keratin-18 and its fragments in liver diseases has drawn increasingly interests in recent years, but studies on its application in chronic hepatitis B is still few. This paper reviews the circulating levels of keratin-18 fragments M30 and M65 in chronic hepatitis B and its application in the future.
Keywords:Cao Zhujun   Liu Kehui   Wang Hui. Department of Infectious Diseases   Shanghai Ruijin Hospital   Shanghai 200025   China Corresponding author : Wang Hui   Email : wanghuirj@ 163. com
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