肌少症对老年胃癌病人术前评估与术后并发症的影响

目的探讨肌少症对老年胃癌病人术前评估与术后并发症的影响。方法回顾性分析2008~2018年南京医科大学附属南京医院收治的102例老年胃癌病人资料,根据有无肌少症分为肌少症组49例和非肌少症组53例。比较2组术前营养状况、术前住院时间、术后并发症发生率、ICU入住率与入住时间、术后住院时间、病死率等指标。结果2组病人术前Hb水平,术后腹腔感染、消化道瘘、2次及以上手术人数比例和病死率的差异均无统计学意义(P>0.05)。肌少症组术前白蛋白、前白蛋白水平低于非肌少症组,术前住院时间、术后ICU入住率、ICU入住时间、通气时间、术后住院时间、肺部感染及胸腔积液的发生率均高于非肌少症组,差异有统计学意义(P<0.05)。结论肌少症可作为老年胃癌病人术前评估的客观指标,术前合并肌少症会增加老年胃癌病人的术后并发症发生率和ICU入住率。

Effect of sarcopenia on preoperative evaluation and postoperative complications in elderly patients with gastric cancer

Objective To investigate the effect of sarcopenia on preoperative evaluation and postoperative complications in the elderly patients with gastric cancer.Methods The clinical data of 102 elderly patients with gastric cancer in Nanjing Hospital Affiliated to Nanjing Medical University from January 2008 to December 2019 were analyzed retrospectively.They were divided into sarcopenia group(n=49)and non-sarcopenia group(n=53).The preoperative nutritional status and hospital stay,postoperative complications,ICU occupancy rate and occupancy time,postoperative hospital stay,mortality were compared between the two groups.Results There were no significant differences in the level of preoperative hemoglobin,the incidence rates of postoperative abdominal infection and gastrointestinal fistula,the number of secondary operations and mortality between the two groups(P>0.05).There were significant differences in the levels of preoperative albumin and prealbumin,the length of preoperative hospital stay and postoperative hospital stay,ICU occupancy rate and occupancy time,postoperative ventilation time,the incidence rates of postoperative pulmonary infection and pleural effusion between the two groups(P<0.05).Conclusions Sarcopenia can be used as an objective index for preoperative evaluation in the elderly patients with gastric cancer.Preoperative sarcopenia will increase the incidence of postoperative complications and ICU occupancy rate in the elderly patients with gastric cancer.