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阿托伐他汀对家族性高胆固醇血症的临床治疗和药理作用
引用本文:杨熙鸿. 阿托伐他汀对家族性高胆固醇血症的临床治疗和药理作用[J]. 临床和实验医学杂志, 2006, 5(9): 1294-1295
作者姓名:杨熙鸿
作者单位:广州市瑞仪生物工程有限公司,广东,广州,510620
摘    要:
目的 用阿托伐他汀治疗家族性高胆固醇血症并对其药理作用进行研究.方法 95 例患者服用阿托伐他汀10 mg/d,疗程一个月,观察其疗效,并分析治疗前后的数据.结果 治疗1 个月后患者病情均有所好转,数据均反映患者的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)下降,高密度脂蛋白(HDL-C)升高,对C反应蛋白(CRP)升高有减低作用.结论 阿托伐他汀能安全有效的治疗家族性高胆固醇血症.

关 键 词:阿托伐他汀  家族性高胆固醇血症  临床治疗  药理作用
修稿时间:2006-08-11

The therapeutical and pharmacological action of atorvastatin for familial hypercholesterolemia
YANG Xi-hong. The therapeutical and pharmacological action of atorvastatin for familial hypercholesterolemia[J]. Journal of Clinical and Experimental Medicine, 2006, 5(9): 1294-1295
Authors:YANG Xi-hong
Affiliation:YANG Xi-hong.Guangzhou Rui-Yi Biological Project Inc. Guangzhou Guangdong 510620,China.
Abstract:
Objectives Atorvastatin was used to treat familial hypercholesterolemia and its pharmacological action was investigated.Methods 95 patients with familial hypercholesterolemia were treated with atorvastatin at the dose of 10mg/d for one month.Results After one month treatment , all the patients took a turn for the better, which was reflected in the decrease in TC, TG, LDL-C and CRP as well as the increase in HDL-C.Conclusion Atorvastatin can be used safely and effectively to treat familial hypercholesterolemia.
Keywords:Atorvastatin  Familial Hypercholesterolemia  Clinical treatment  Pharmacological action
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