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Two new flavonoids from Centella asiatica (Linn.)
Authors:Ravi Subban  A Veerakumar  R Manimaran  K M Hashim  Indira Balachandran
Institution:(1) Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, Kerala, India, 676503;(2) JSS College of Pharmacy, Udhagamandalam, Nilgiris, Tamilnadu, India, 643001
Abstract:Two new flavonoids named castilliferol 1 and castillicetin 2, as well as a known compound, isochlorogenic acid 3, were isolated from the whole plant of Centella asiatica. Isolates 1 and 2 exhibited good antioxidant activity using 2,2-diphenyl-1-picryl hydrazyl radical solution with IC50 values of 23.10 and 13.30, respectively. The structures of these isolates were determined by analytical and spectral data, including 1-D and 2-D NMR spectra.
Keywords:Apiaceae            Centella asiatica            Castilliferol  Castillicetin  Isochlorogenic acid
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