Two new flavonoids from Centella asiatica (Linn.) |
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Authors: | Ravi Subban A Veerakumar R Manimaran K M Hashim Indira Balachandran |
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Institution: | (1) Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, Kerala, India, 676503;(2) JSS College of Pharmacy, Udhagamandalam, Nilgiris, Tamilnadu, India, 643001 |
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Abstract: | Two new flavonoids named castilliferol 1 and castillicetin 2, as well as a known compound, isochlorogenic acid 3, were isolated from the whole plant of Centella asiatica. Isolates 1 and 2 exhibited good antioxidant activity using 2,2-diphenyl-1-picryl hydrazyl radical solution with IC50 values of 23.10 and 13.30, respectively. The structures of these isolates were determined by analytical and spectral data,
including 1-D and 2-D NMR spectra. |
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Keywords: | Apiaceae Centella asiatica Castilliferol Castillicetin Isochlorogenic acid |
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