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| CD_4~+CD_(25)~+调节性T细胞和树突状细胞在HBV感染中的相互作用 | |
| 引用本文： | 周培培,徐娟. CD_4~+CD_(25)~+调节性T细胞和树突状细胞在HBV感染中的相互作用[J]. 医学综述, 2011, 17(1): 4-7 |
| 作者姓名： | 周培培 徐娟 |
| 作者单位： | 1. 新泰市人民医院感染病科,江苏,新泰,271200 2. 徐州医学院附属医院感染病科,江苏,徐州,221002 |
| 基金项目： | 江苏省卫生厅课题，江苏省高校自然科学基金，2008年江苏省高校"青蓝工程"中青年学术带头人培养基金 |
| 摘 要： | CD4+CD25+调节性T细胞(Treg)是迄今为止所发现的最重要的免疫抑制细胞,几乎抑制所有的免疫反应,在机体免疫系统中发挥负向调节作用。树突状细胞(DC)作为一类专职的抗原递呈细胞,在抗原识别、递呈中发挥重要作用,具有启动免疫应答和诱导免疫耐受的双重特性,对机体抗乙型肝炎病毒(HBV)起关键作用。作为在HBV致病机制中起重要作用的两个免疫细胞群——Treg与DC,探讨二者在慢性乙型肝炎发病机制中的相互作用,必将为进一步探索治疗HBV提供新的思路。 |
| 关 键 词： | CD4+CD25+调节性T细胞 树突状细胞 乙型肝炎病毒 |
Cross-talk between CD4 +CD25 + Regulatory T Cells and Dendritic Cells in Patients with HBV Infection |
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| ZHOU Pei-pei,XU Juan. Cross-talk between CD4 +CD25 + Regulatory T Cells and Dendritic Cells in Patients with HBV Infection[J]. Medical Recapitulate, 2011, 17(1): 4-7 | |
| Authors: | ZHOU Pei-pei XU Juan |
| Affiliation: | 1.Department of Infectious Diseases,the People′s Hospital of Xintai,Xintai 271200,China;2.Department of Infectious Diseases,the First Affiliated Hospital of Xuzhou Medical College,Xuzhou 221002,China) |
| Abstract: | CD4+CD25+ regulatory cell(Treg)is one of an important immune supression cells among dicscoverable immune cells,which almost suppress all immune reaction and take negative regulatory function.Dendritic cell(DC)is one of full-time antigen presenting cell,which conducts its function in antigen recongnition and presantation,posses double characteristics in starting immune reaction and induing mimune tolerance,and also play key role in anti-hepatitis B virus(HBV).As two important cells Treg and DC in the pathoge... |
| Keywords: | CD4 CD25 T regulatory cells Dendritic cells Hepatitis B virus |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |