磁敏感加权成像时弥漫性轴索损伤的诊断价值

目的 分析弥漫性轴索损失（DAI）的MRI表现,探讨磁敏感加权成像（SWI）对DAI的诊断价值.方法 回顾性分析30例临床诊断为DAI患者的MRI图像,比较病灶在各序列的显示率,并分析其信号特征及分布部位.结果 T1WI序列显示率较低,其次为T2WI序列,显示者T1WI为低信号,T2WI为高信号,FLAIR序列敏感性较高,显示者为片状、斑片状高信号,病灶越小显示越不敏感,SWI序列显示病灶更多、更敏感,病灶主要分布在皮髓质交界区、基底节、胼胝体、脑干及小脑上脚等,呈散在针尖状、小片状或片状显著低信号.结论 相比常规MR序列,SWI序列对DAI病灶检出率更高,可为DAI作出准确诊断,对临床怀疑为DAI患者,SWI序列可作为常规MR序列的重要补充.

Diagnostic value of susceptibility weighted image in diffuse axonal injury

Objective To investigate the value of SWI sequence in diagnosis of DAI by analyzing the MRI images of DAI. Methods The MRI data of 30 cases with DAI diagnosed by clinic were analyzed retrospectively. The signal intensity features and detection rate of lesions were compared in all sequences. Results SE TIWI sequence had the lowest sensitivity, secondly was T2W1 sequence. DAI showed as long T1 long T2 signal. Some lesions could be detected with FLAIR, appearing as nodular or patchy hyper- intensity. More lesions were detected with SWI sequence than with other sequences. DAI lesions mainly located in the junctional zone of cortex and medulla, basal ganglia, corpus callosum, brain stem and cerebelluIn. It appeared as needle tip, mottling, nodular hypointensity in SWI sequence. Conclusion SWI can detect more lesions in cases with DAI than other sequences. It can be an additional sequence in MRI examination for the patients suspicioused with DAL