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Late results of the Cox-maze IV procedure in patients undergoing coronary artery bypass grafting
Authors:Matthew R. Schill  Farah N. Musharbash  Vivek Hansalia  Jason W. Greenberg  Spencer J. Melby  Hersh S. Maniar  Laurie A. Sinn  Richard B. Schuessler  Marc R. Moon  Ralph J. Damiano
Affiliation:Division of Cardiothoracic Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, St Louis, Mo
Abstract:

Objective

Most patients with atrial fibrillation (AF) undergoing cardiac surgery do not receive concomitant ablation. This study reviewed outcomes of patients with AF undergoing Cox-maze IV (CMIV) procedure with radiofrequency and cryoablation and coronary artery bypass grafting (CABG) at our institution.

Methods

Between the introduction of radiofrequency ablation in 2002 and 2015, 135 patients underwent left- or biatrial CMIV with CABG. Patients undergoing other cardiac procedures, except mitral valve repair, or who had emergent, reoperative, or off-pump procedures were excluded. Eighty-three patients remained in the study group after exclusion criteria were applied. Freedom from atrial tachyarrhythmias (ATAs) was ascertained using electrocardiogram, Holter monitor, or pacemaker interrogation at 1 to 5 years postoperatively.

Results

Operative mortality was 3%. Freedom from ATAs at 1 year in the CMIV group was 98%, with 88% off antiarrhythmia drugs. Freedom from ATAs and antiarrhythmia drugs was 70% at 5 years.

Conclusions

The addition of CMIV to CABG resulted in excellent freedom from ATAs at 1 to 5 years. These patients are at increased risk for nonfatal complications compared with others undergoing concomitant surgical ablation.
Keywords:atrial fibrillation  arrhythmia therapy  ablation  coronary artery bypass grafting  AAD  anti-arrhythmia drugs  AC  anticoagulation  AF  atrial fibrillation  ATA  atrial tachyarrhythmias  CMIV  Cox-maze IV  CABG  coronary artery bypass grafting  STS  Society of Thoracic Surgeons
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