| 肝胆结石片的镇痛,解热及利尿作用 |
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| 引用本文： | 万尧 廖雪松. 肝胆结石片的镇痛,解热及利尿作用[J]. 中国药房, 1999, 10(1): 12-13 |
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| 作者姓名： | 万尧 廖雪松 |
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| 作者单位： | 四川省中药研究所,重庆市第三人民医院检验科,重庆通合应用科技情报所 |
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| 摘 要： | ｉｇ肝胆结石片３．０、１．５ｇ（生药）／ｋｇ对醋酸所致小鼠的扭体反应抑制率分别为４２．８％、３９．２％;ｉｇ药后１５ｍｉｎ对甲醛所致小鼠的舔足反应的抑制率分别为５２．９％、３５．３％;３０ｍｉｎ的舐足抑制率分别为６８．０％、２３．３％均有显著的镇痛作用;对角叉菜胶致大鼠的升温时程曲线有显著的降低作用。且能促进大鼠尿排量的增加,增加率分别为２０７％、１４７％,表现出良好的利湿作用。
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| 关 键 词： | 肝胆结石片 镇痛 解热 利尿 |
The Analgesic ,Antipyretic and Diuretic Effects of Gandan Jieshi Tablet(GJ) |
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| WAN Yaode,WAN Dongmei. The Analgesic ,Antipyretic and Diuretic Effects of Gandan Jieshi Tablet(GJ)[J]. China Pharmacy, 1999, 10(1): 12-13 |
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| Authors: | WAN Yaode WAN Dongmei |
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| Abstract: | The results showed that GJ ,orally given in dose of 1. 5g/(kg . d) ,3. 0g/(kg . d) ,could decrease 42. 8% ,39. 2% ofwrithing reaction induced by acetic acid in mice respectively, and decrease 52.9% , 35.2% of and 68.0% , 23.3% of Licking pawsreaction induced by foumaldbyde in mice alter 15 mins and after 30 mins, respectively. The results showed its marked analgesic ef-fect. In addition,GJ could significantly reduce time - course curve of body temperature increase induced by carrageenin in rats. It couldincrease urine volume of rats showing that GJ has satisfactory diuretic effect. |
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| Keywords: | Gandan Jieshi tablet analgesic effect antipyretic effect diuretic |
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