Chlamydial etiology of acute lower respiratory tract infections in children in the Sudan |
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| Authors: | B Herrmann,MAM Salih,BE Yousif,O Abdelwahab,P-A Må rdh |
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| Affiliation: | Institute of Clinical Bacteriology, University of Uppsala, Uppsala, Sweden;Department of Pediatrics, Faculty of Medicine, University of Khartoum, Khartoum, Sudan;Department of Pediatrics, Khartoum Teaching Hospital, Khartoum, Sudan;Department of Radiology, Khartoum Teaching Hospital, Khartoum, Sudan |
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| Abstract: | The role of Chlamydia pneumoniae in 110 Sudanese children with signs of acute lower respiratory tract infections (ALRI) was investigated. Four (3.6%) had evidence of C. pneumoniae infection, of whom 3 were culture-positive, while 1 had an antibody response suggesting a recent infection. IgG antibodies at a titer of ≥1:32 to C. pneumoniae, Chlamydia psittaci and Chlamydia trachomatis were detected in 27 (24.5%), 27 (24.5%) and 7 (6.4%) of the 110 ALRI cases, respectively. C. pneumoniae, C. trachomatis or C. psittaci were not detected in nasopharyngeal secretions from any of 110 patients when fluorescence-labeled specific monoclonal antibodies were used. In a seroepidemiological survey, 318 healthy Sudanese persons aged between 1 month and 67 years were studied for C. pneumoniae antibodies. |
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| Keywords: | Children chlamydia respiratory infections |
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