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| 国产利福昔明治疗急性细菌性肠道感染随机对照试验的Meta分析 | |
| 引用本文： | 方宝霞,陈富超,李鹏,时晓亚. 国产利福昔明治疗急性细菌性肠道感染随机对照试验的Meta分析[J]. 中国药物应用与监测, 2010, 7(2): 76-79 |
| 作者姓名： | 方宝霞 陈富超 李鹏 时晓亚 |
| 作者单位： | 郧阳医学院附属东风总医院药学部,湖北,十堰,442008 |
| 摘 要： | 目的：探讨国产利福昔明治疗急性细菌性肠道感染的有效性和安全性。方法：按照系统评价的要求,全面检索了1994年1月-2008年12月中国医院数字图书馆、中文科技期刊数据库,对符合纳入标准的l5篇文献共计2443名患者的相关疗效指标进行了Meta分析。结果：与环丙沙星、左氧氟沙星相比,国产利福昔明治疗急性细菌性肠道感染的痊愈率、有效率、细菌清除率差异均无统计学意义（P〉0.05）;国产利福昔明不良反应发生率为3.29%（39/1184）,与对照药物比较差异无统计学意义[OR合并=0.93,95%CI为0.60～1.44,P=0.74]。结论：目前国内证据表明,与环丙沙星、左氧氟沙星相比,国产利福昔明治疗急性细菌性肠道感染疗效无显著性差异。 |
| 关 键 词： | 利福昔明 随机对照试验 细菌性肠道感染 Meta分析 |
Meta-analysis on randomized control trials of indigenous rifaximin in the treatment of acute infectious diarrhea |
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| FANG Bao-xia,CHEN Fu-chao,LI Peng,SHI Xiao-ya. Meta-analysis on randomized control trials of indigenous rifaximin in the treatment of acute infectious diarrhea[J]. , 2010, 7(2): 76-79 | |
| Authors: | FANG Bao-xia CHEN Fu-chao LI Peng SHI Xiao-ya |
| Affiliation: | FANG Bao-xia,CHEN Fu-chao,LI Peng,SHI Xiao-ya(Department of Pharmacy,Dongfeng General Hospital Affiliated to Yunyang Medical College,Shiyan 442008,China) |
| Abstract: | Objective:To estimate the efficacy and safety of indigenous rifaximin in the treatment of acute infectious diarrhea. Methods: Based on the principles and methods of systematic reviews, we searched Chinese Hospital Digital Database and VIP from January 1994 to December 2008. Meta-analysis was performed on the related clinical indexes of 2443 patients involved in 15 papers which met the inclusion criteria. Results: The clinical cure rates, clinical effective rates, corresponding bacterial eradication rates of... |
| Keywords: | Rifaximin Randomized control trial Infectious diarrhea Meta-analysis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |