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杜仲叶的药理作用研究进展
引用本文:袁天翊,方莲花,吕扬,杜冠华.杜仲叶的药理作用研究进展[J].中国中药杂志,2013,38(6):781-785.
作者姓名:袁天翊  方莲花  吕扬  杜冠华
作者单位:中国医学科学院北京协和医学院 药物研究所北京市药物靶点研究与新药筛选重点实验室,北京,100050
基金项目:国家"重大新药创制"科技重大专项(2013ZX09103001-008);科技部基础性工作专项重点项目(2007FY130100)
摘    要:杜仲Eucommia ulmoides是中国名贵滋补药材,由于一直以来以皮入药,加上资源较为稀缺,因此人们开始以杜仲叶Eucommiae Folium代替杜仲皮入药.杜仲及杜仲叶具有多种药理活性,且在临床上也有一定的应用,是极具开发价值的道地中药材.现代药理研究表明,杜仲叶具有降压、调节血脂、心血管保护、预防肥胖、抗炎、抗病毒、增强免疫、延缓衰老、抗疲劳等作用.临床上杜仲叶主要应用于降压、治疗妇产科疾病等.笔者对杜仲叶的药理作用及临床应用的国内外最新研究现状作一综述,为杜仲叶的新药研究开发提供参考.

关 键 词:杜仲  杜仲叶  药理作用
收稿时间:1/9/2012 12:00:00 AM

Advance in study on pharmacological effect of Eucommiae Folium
YUAN Tian-yi,FANG Lian-hu,LV Yang and DU Guan-hua.Advance in study on pharmacological effect of Eucommiae Folium[J].China Journal of Chinese Materia Medica,2013,38(6):781-785.
Authors:YUAN Tian-yi  FANG Lian-hu  LV Yang and DU Guan-hua
Institution:Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100050, China;Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100050, China;Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100050, China;Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100050, China
Abstract:Eucommia ulmoides is a valuable traditional Chinese medicine, whose cortexes have long been used as medicines.Due to the scarcity of its resources, people began using its leaves instead of cortexes in medicines.Eucommiae Folium and its leaves have many pharmacological effects and thereby being clinically applied as genuine traditional Chinese medicines.Modern pharmological studies have showed that Eucommiae Folium leaves have such effects as blood pressure reduction, blood lipid regulation, cardiovascular protection, anti-obesity, anti-inflammation, anti-virus, enhancement of immunologic function, resistance against senility and anti-fatigue.In clinic, Eucommiae Folium is mainly used to treat hypertention and obstetrical and gynecological disease.The essay summarizes the latest advance in domestic and foreign studies on pharmacological effects and clinical applications of Eucommiae Folium leaves, and thus providing reference for studies on new drugs of Eucommiae Folium leave.
Keywords:Eucommia ulmoides  Eucommiae Folium  pharmacological effect
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