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仙人掌提取物对小鼠T淋巴细胞增殖的影响
引用本文:毛泽善,徐自超,马全祥,袁向山,毛腾飞,杨雪丽. 仙人掌提取物对小鼠T淋巴细胞增殖的影响[J]. 新乡医学院学报, 2006, 23(6): 548-549
作者姓名:毛泽善  徐自超  马全祥  袁向山  毛腾飞  杨雪丽
作者单位:1. 新乡医学院形态学实验室,河南,新乡,453003
2. 新乡医学院学报编辑部,河南,新乡,453003
3. 新乡医学院组织胚胎学教研室,河南,新乡,453003
4. 新乡医学院生物技术系本科2004级,河南,新乡,453003
5. 新乡医学院2003级本科,河南,新乡,453003
摘    要:目的探讨仙人掌提取物对小鼠T淋巴细胞增殖的影响。方法将30只小鼠随机等分为空白对照组、实验组和阳性对照组。空白对照组用生理盐水20mg·kg-1灌胃,实验组用仙人掌提取物5mg·kg-1灌胃,阳性对照组用胸腺肽5mg/只灌胃,每日1次,10d后酶染法检测外周血酸性α-醋酸萘酯(ANAE)阳性率,MTT法检测小鼠胸腺T淋巴细胞增殖。结果与空白对照组相比,实验组小鼠外周血ANAE阳性率增高、胸腺T淋巴细胞增殖明显(P<0.05),与阳性对照组比较则无显著差异(P>0.05)。结论仙人掌提取物对小鼠T淋巴细胞的增殖有促进作用。

关 键 词:仙人掌提取物  小鼠  酸性α-醋酸萘酯  T淋巴细胞
文章编号:1004-7239(2006)06-0548-02
收稿时间:2006-05-31
修稿时间:2006-05-31

Effects of extract of Cactus on the proliferate of T-lymphocyte in mice
MAO Ze-shan,XU Zi-Chao,MA Quan-xiang,et al. Effects of extract of Cactus on the proliferate of T-lymphocyte in mice[J]. Journal of Xinxiang Medical College, 2006, 23(6): 548-549
Authors:MAO Ze-shan  XU Zi-Chao  MA Quan-xiang  et al
Abstract:Objective To observe the effect of extract of Cactus on the proliferate of T-lymphocyte in mice.Methods Thirty mice were randomly divided into three groups: the normal control group, the experimental group and the positive control group. Saline ig was given in mice of the normal control group,with Cactus-extract(5 mg·kg~ -1 ) ig were given in mice of the experiment group,and the thymopeptide was given in mice of the positive control group,for 10 days in all three group. The changes of acid-a-naphthalene acetate( ANAE) positive rate and proliferation of T-lymphocyte with MTT test.Results Compared to the control group, ANAE positive rate and proliferation of T-lymphocyte increased significantely in the experimental group(P<0.05).Conclusion Cactus-extract plays an important role of promote on the proliferate of T-lymphocyte in mice.
Keywords:Cactus-extract   rat   acid-α-naphthalene acetate esterase   T-lymphocyte
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