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炎症对上皮间质转化的调控机制
引用本文:单泽志,严雪冰,金志明. 炎症对上皮间质转化的调控机制[J]. 国际肿瘤学杂志, 2014, 41(2): 90-93
作者姓名:单泽志  严雪冰  金志明
作者单位:200233 上海交通大学附属第六人民医院普外科
摘    要:
炎症在肿瘤发生发展中发挥重要作用.上皮间质转化(EMT)是肿瘤增殖、侵袭及转移过程中的重要分子机制.越来越多的研究表明,炎症与EMT密切相关.在炎症微环境中,细胞因子和炎症微生物都参与EMT的调控.

关 键 词:炎症  肿瘤侵润  肿瘤转移  上皮间质转化
收稿时间:2013-09-29;

Regulatory mechanisms of inflammation in epithelial mesenchymal transition
Shan Zezhi,Yan Xuebing,Jin Zhiming. Regulatory mechanisms of inflammation in epithelial mesenchymal transition[J]. Journal of International Oncology, 2014, 41(2): 90-93
Authors:Shan Zezhi  Yan Xuebing  Jin Zhiming
Affiliation:Department of General Surgery, Sixth People′s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China
Abstract:
Inflammation plays an important role in the initiation and development of tumor. Epithelial mesenchymal transition (EMT) acts as a critical molecular mechanism involved in the proliferation, invasion and metastasis of tumor. Mounting studies show that inflammation is related with EMT closely. In the inflammatory microenvironment, both cytokines and microbes take part in the regulation of EMT.
Keywords:Inflammation  Neoplasm invasiveness  Neoplasm metastasis  Epithelial mesenchymal transition
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