The expression of nuclear factor kappa B in cancer cells of human adenocarcinoma] |
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| Authors: | Yao Chen Ruixiang Li |
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| Affiliation: | Department of Anatomy, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China. |
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| Abstract: | OBJECTIVE: Nuclear factor kappa B is very important in cis-activation which regulates the expression of many genes. This study inquired into the mechanism of cancer cell metastasis. METHODS: Immunohistochemical method was used for studying the expression of nuclear factor kappa B in cancer cells of human metastasized rectum adenocarcinoma. RESULTS: Expressed nuclear factor kappa Bp65 was found in the cancer cells of peritumoral tissues and metastasized lymph nodes. The reaction product was located in the cytoplasm and cytonucleus. CONCLUSION: The findings of this study suggest a strong correlation between the expression of nuclear factor kappa B in cancer cells and the metastasis of cancer. |
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