| 咳嗽变异性哮喘与气道重塑 |
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| 引用本文： | 祝筱姬,孟晓,徐睿.咳嗽变异性哮喘与气道重塑[J].国际呼吸杂志,2014,0(7):531-535. |
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| 作者姓名： | 祝筱姬 孟晓 徐睿 |
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| 作者单位： | 祝筱姬(解放军第 89 医院呼吸内科, 潍坊,261021)；孟晓(解放军第 89 医院呼吸内科, 潍坊,261021)；徐睿(解放军第 89 医院呼吸内科, 潍坊,261021)； |
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| 摘 要： | 咳嗽变异性哮喘（coughvariantasthma，CVA）是指以慢性咳嗽为主要或唯一症状的一种特殊类型哮喘，其病理生理改变与典型哮喘相同，若未及时诊治，约30％～40％可发展成为典型哮喘。气道炎细胞浸润和气道重塑是CVA的病理基础。CVA可称之为一种隐匿性哮喘，常被临床医师所忽略，患者失去正确的诊断与治疗。正确认识CVA的病理生理特征，对临床诊断和治疗具有重要的指导意义，可降低典型哮喘的发病率。本文就CVA与气道炎性反应和气道重塑的关系作一综述。
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| 关 键 词： | 咳嗽变异性哮喘 哮喘 细胞浸润 气道重塑 |
Cough variant asthma and airway remodeling |
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| Zhu Xiaoji,Meng Xiao,Xu Rui.Cough variant asthma and airway remodeling[J].International Journal of Respiration,2014,0(7):531-535. |
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| Authors: | Zhu Xiaoji Meng Xiao Xu Rui |
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| Institution: | . Department ofRespiratory Medicine ,the 89th Hospital of PLA ,Weifang 261021 ,China |
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| Abstract: | Cough variant asthma（CVA） is a special typologic bronchial asthma （asthma） which presents solely with chronic cough. CVA is a form of asthma,CVA shares a number of pathophysiological features with classic asthma. More importantly, 30% to 40% of adult patients with CVA, unless adequately treated, may progress to classic asthma. Cellular infiltration and airway remodeling are pathological basis of CVA. CVA may call an insidious asthma,it was neglected freguently by clinician, and the patients were missed correct diagnosis and treatment. To know correctly pathophysiological features of CVA,it is important significance for clinical treatment,and may decrease incidence of asthma. In this review,we analyzed the correlation between CVA and inflammatory reaction,airway remodeling. |
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| Keywords: | Cough variant asthma Asthma Cellular infiltration Airway remodeling |
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