| 久坐行为与心血管疾病风险 |
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| 引用本文： | 丁季喆,马恒,王一石.久坐行为与心血管疾病风险[J].心脏杂志,2021,33(3):330-334. |
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| 作者姓名： | 丁季喆 马恒 王一石 |
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| 作者单位： | 1.学员二大队 空军军医大学基础医学院 |
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| 基金项目： | 国家自然科学基金项目资助（82070261）；陕西省国际合作交流项目资助（2015KW-050） |
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| 摘 要： | 久坐行为（sedentary behavior）有损人体健康。以往的研究主要围绕在久坐与全因死亡和/或代谢障碍之间的关系，然而久坐与心血管疾病（cardiovascular disease，CVD）发展之间的关系尚待深入研究。本文就久坐行为对心血管系统疾病的影响进行综述，分析久坐行为对关键生物学过程，如:血流动力学、炎症、氧化应激损伤以及衰老的影响，并探讨其中的可能机制。推动针对久坐行为制定公共健康指南。
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| 关 键 词： | 久坐 运动 心血管疾病 公共健康 |
| 收稿时间： | 2021-04-13 |
Sedentary behavior and cardiovascular health risk |
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| Institution: | 1.Second Cadet Regiment2.Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Air Force Medical University, Xi’an 710032, Shaanxi, China |
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| Abstract: | Sedentary behavior is harmful to human health. Previous studies mainly focused on the relationship between sedentary behavior and all-cause mortality or metabolic disorders, while the connection between sedentary behavior and the development of cardiovascular disease is needed to be further discussed. This review mainly discusses the mechanisms linking sedentary behavior to CVD risk, analyzes the effect that sedentary behavior has on hemodynamics, inflammation, oxidative stress, aging, etc., and presents an overview of studies that explore the underlying mechanisms of the connection between sedentary behavior and the development of cardiovascular disease. There is an urgent need for public health guidelines on physical activity and sedentary behavior. |
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