5-氨基酮戊酸-光动力疗法治疗尖锐湿疣临床观察

目的 观察5-氨基酮戊酸-光动力疗法(ALA-PDT)治疗尖锐湿疣的疗效和安全性.方法 外生殖部尖锐湿疣患者28例,先后2次将5% ALA霜涂于病变处及其周围5 mm范围皮肤黏膜上,间隔2 h.第2次涂ALA霜后2 h,以功率300 mW、光斑直径15～20 mm、时间20 min、能量密度100 J/cm2、波长635nm半导体激光照射病损区.1周后判定疗效,随访1～3个月观察复发情况.结果 28例患者经过1～2次治疗后治愈26例,治愈率92.9%.随访3个月,复发9例,复发率34.6%.多数患者治疗后局部出现轻度水肿.结论 ALA-PDT可有效治疗外生殖器尖锐湿疣,降低皮损复发率,且不良反应少.

ALA-PDT to Condyloma Acuminatum:Clinical Observation for Treatment Effects

Objective To observe treatment effects and security of ALA-PDT to genital warts.Methods Twenty-eight condyloma acuminatum patients were treated with ALA-PDT for 1-2 times.The treatment effects and side effects were observed respectively after 1 week.And the recurrence rates were counted after 3 months.Results After 1-2 times photodynamic treatment,the healing rate was 92.9%.And the recurrence rate was 34.6% after 3 months.The most common local side effect was mild edema and erosion.Conclusions With the adva...