儿童维生素A与铁营养状况的相关性研究

目的了解中国儿童维生素A(VA)的营养状况、VA缺乏率、VA边缘缺乏率,研究血浆VA与铁营养状况的相关性。方法由2002年“中国居民营养与健康状况调查”的大样本中随机抽取380名3~12岁儿童,检测血浆VA含量,同时测定血红蛋白(Hb)、总铁结合力(TIBC)、铁蛋白(SF)及转铁蛋白受体(sTfR)。了解儿童VA营养状况,计算VA缺乏率、VA边缘缺乏率,研究VA与铁营养状况评价指标的相关性。结果受试儿童VA平均含量为(1·03±0·24)μmol/L,其中8·4%儿童VA缺乏,44·7%儿童VA边缘缺乏。血浆VA与Hb呈正相关(r=0·16986,P<0·01),与sTfR呈负相关(r=-0·12863,P<0·05),与TIBC、SF不相关。结论铁缺乏伴随VA边缘缺乏在中国儿童中普遍存在,VA与铁营养状况存在相关性。

Study on the correlation of vitamin A and iron status in children

OBJECTIVE: To study vitamin A status, the prevalence of vitamin A (VA) deficiency and marginal VA deficiency and the correlation of VA and iron status of Chinese children. METHODS: 380 children were randomly chosen from "Survey on the Status of Nutrition and Health of the Chinese People" (CNHS) in 2002. The plasma vitamin A, hemoglobin (Hb), total iron-binding capacity (TIBC), ferritin (SF) and soluble transferrin receptor (sTfR) were detected. The prevalence of VA deficiency and marginal deficiency was assessed and the correlation of VA and iron indexes was studied. RESULTS: The VA concentration of subjects was (1.03 +/- 0.24) micromol/L. The prevalence of VA deficiency and VA marginal deficient was 8.4% and 44.7% respectively. Plasma VA was positively correlated with Hb (r = 0.16986, P < 0.01) and negatively correlated with sTfR (r = -0.12863, P < 0.05) significantly but there was no association of SF and TIBC. CONCLUSION: Iron deficiency coexisted VA marginal deficiency are still very prevalent in Chinese children, plasma VA are correlated with iron status.