Post-operative adhesions after laparoscopic electrosurgical treatment for polycystic ovarian syndrome with the application of Interceed to one ovary: a prospective randomized controlled study

In this prospective, randomized, controlled clinical study,21 women underwent a second-look laparoscopy 2–11 weeksafter standardized laparoscopic electrosurgical treatment forpolycystic ovarian syndrome (PCOS). Following bilateral ovariantreatment, one ovary was randomly chosen to have Interceed appliedto its surface using a specially designed applicator, with theother ovary serving as a control. Peri-adnexal adhesions ofsignificant extent and severity developed in 57% of the womenand 38% of the adnexa. The incidence of adhesions on the Interceed-treatedside was 43%, while on the control side it was 33%. In addition,the extent and severity of the adhesions appeared to be similaron the Interceed-treated and the control side. However, largernumbers would be required to determine statistically the effectsof Interceed on de-novo adhesion formation after laparoscopicelectro-surgical treatment of PCOS, as described here.