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从肝探析复发性口腔溃疡病因
引用本文:王曼,兰天宇,李皓皓,陈嘉辉,尤艳利. 从肝探析复发性口腔溃疡病因[J]. 河南中医, 2017, 37(6). DOI: 10.16367/j.issn.1003-5028.2017.06.0363
作者姓名:王曼  兰天宇  李皓皓  陈嘉辉  尤艳利
作者单位:第二军医大学附属长海医院,上海,200433
基金项目:国家大学生创新基金项目,国家大学生孵化基地基金项目
摘    要:
肝经及其分支通过直接循行入口或与脾经、胃经交会的方式影响着口腔溃疡的发生。肝经经气异常会导致肝血不足,肝气升降失司,气血不和,诸病皆起,在口则表现为溃疡的反复发作。肝气升发太过或疏泄不及都易致情志病,这些负性心理因素抑制人体内与溃疡相关的蛋白质的表达与调节,诱发口腔溃疡并影响其修复。肝胆相互表里、同居中焦,共具枢转气机功能。若疏泄失常,则脾胃之气升降异常,运化失司,聚湿生热导致口舌生疮。肝失疏泄亦可母病及子,累及于心,上达口舌,发为溃疡。"女子以肝为先天",肝主藏血,肝血是月经来潮的重要保证,肝脏对经期体内各种激素水平的变化有重要调控作用,基于此,经行口糜这类特殊的口腔溃疡亦须从肝论治。免疫功能异常和微量元素缺乏同样被认为是引起复发性口腔溃疡的重要因素,这两者又与肝脏相互影响。总之,无论从中医学还是现代医学角度分析,肝与复发性口腔溃疡的发生发展之间都存在着密切的关系。因此,从肝探析复发性口腔溃疡的病因具有现实意义,为临床防治复发性口腔溃疡提供了重要的参考。

关 键 词:复发性口腔溃疡  从肝探析  病因

Exploration of Etiology of Recurrent Oral Ulcer by Analyzing the Liver
WANG Man,LAN Tian-yu,LI Hao-hao,CHEN Jia-hui,YOU Yan-li. Exploration of Etiology of Recurrent Oral Ulcer by Analyzing the Liver[J]. Henan Traditional Chinese Medicine, 2017, 37(6). DOI: 10.16367/j.issn.1003-5028.2017.06.0363
Authors:WANG Man  LAN Tian-yu  LI Hao-hao  CHEN Jia-hui  YOU Yan-li
Abstract:
The liver meridian and its branches affects the incidence of oral ulcer through direct circulation into the mouth or the intersection with the spleen meridian and stomach meridian.Abnormal liver meridian qi leads to liver blood deficiency.If liver qi fails to control ascending and descending qi,disharmony of qi and blood,all kinds of diseases will appear,and recurrent oral ulcer will occur in the mouth.Too much lifting of liver qi or deficient dispersing of it easily leads to emotional diseases;These negative psychological factors inhibit the expression and regulation of protein related to oral ulcer inside the body,induce oral ulcer,and affect its repair.Both liver and gall being mutually exterior and interior lie in the middle energizer,control functions of qi activity.If dispersing is abnormal,ascending and descending of spleen-stomach qi and transformation will also become abnormal,accumulated dampness generates heat and lead to oral ulcer.Due to disorder of mother-organ involving its child-organ,abnormal liver dispersing affects the heart,then the mouth and tongue,so oral ulcer occurs." The liver is women's congenital foundation".The liver stores blood,liver blood is an important guarantee for menstruation;The liver has an important role in regulating hormone levels changes in menstrual period.On the basis of this,the erosion of the mouth of this special class of oral ulcer should be treated from the liver.Abnormal immune function and micronutrient deficiency are also considered as important factors causing recurrent aphthous ulcers,both of which interact with the liver.In conclusion,there is a close relationship between the liver and the occurrence and development of recurrent oral ulcer,whether it is from the angle of traditional Chinese medicine or modern medicine.Therefore,it is of practical significance to analyze the etiology of recurrent oral ulcers from the liver and provide an important reference for the prevention and treatment of recurrent aphthous ulcers.
Keywords:recurrent oral ulcer (ROU)  analysis of liver  etiology
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