中西医结合治疗糖尿病肾病35例

目的:观察中西医结合治疗糖尿病肾病的临床疗效。方法:选择2014年4月—2015年4月本院收治的70例糖尿病肾病患者,随机分为对照组和观察组,每组各35例。对照组给予厄贝沙坦,观察组在对照组的基础上口服复方丹参滴丸。观察两组患者治疗前后肾功能检测指标、血液流变学指标及不良反应发生率。结果:两组患者治疗后血尿素氮(blood urea nitrogen,BUN)、肌酐(serum creatinine,Scr)、尿β2-微球蛋白(β2-Microsphere protein,β2-MG)及24 h尿蛋白定量水平较治疗前明显下降,且观察组低于对照组,具有显著性差异(P0.05)。两组患者治疗后血液流变学各项指标较治疗前明显下降,且观察组低于对照组,具有显著性差异(P0.05)。观察组不良反应发生较低于对照组,具有显著性差异(P0.05)。结论:中西医结合治疗糖尿病肾病,可明显改善肾功能指标和血液流变学指标,降低不良反应。

Thirty-Five Cases of Patients with Diabetic Nephropathy Treated with Combined Therapy of Traditional Chinese and Western Medicine

Objective:To observe the clinical curative effect of combined therapy of traditional Chinese and Western medicine on patients with diabetic nephropathy (DN).Methods:Seventy patients with DN who were treated in our hospital between April of 2014 and April of 2015 were chosen as the research subjects,and were randomly divided into the control group and the observation group,with 35 cases in each group.The ones in the control group were treated with Irbesartan,while the ones in the observation group were added Compound Danshen Dripping Pills based on the treatment of the control group.Then the two groups' indexes of renal function,blood rheology and the incidence of adverse reactions were observed.Results:After the treatment,the levels of Scr,BUN,beta 2-MG and 24 h urinary protein in two groups were significantly lower than those before the treatment,and the observation group was lower than the control group,and the difference between them had significance (P ＜ 0.05).Their indexes of hemorheology were significantly decreased compared with before the treatment,and the observation group was lower than the control group,and the difference between them had significance (P ＜ 0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference between them had significance (P ＜ 0.05).Conclusion:In terms of treating DN,combined therapy of traditional Chinese and Western medicine can significantly improve the renal function and blood rheology index,and reduce adverse reactions.