基于 Medline 收录的 Brugada 综合征相关研究的文献计量分析

目的：总结分析 Brugada 综合征（Brugada syndrome，BrS）相关研究文献的分布特点。方法以 GoPubMed 为检索工具，检索 Medline 数据库中收录的 BrS 相关的研究文献（1992－01－01—2015－12－31），并对文献发表的时间、地域、期刊及研究主题等分布特征进行计量分析。结果共检索到相关文献2220篇，文献数量自1998年后呈逐渐上升趋势，近3年达到相对的研究高峰。文献发表量排名前三位的国家依次是美国（386篇，17．39％）、日本（353篇，15．90％）、法国（133篇，5．99％），中国排在第11位（53篇，2．39％）。发文量居前三位的城市依次为荷兰阿姆斯特丹（80篇）、日本东京（70篇）、美国尤蒂卡（58篇）。中国城市中，北京发文最多，全球排名第36位（13篇）；南京、广州次之，全球排名并列第43位（7篇）。前三位杂志分布依次是 Heart Rhythm（144篇）、Journal of Cardiovasular Electrophysiology（143篇）、Pacing and Clinical Electrophysiology（90篇），三者占发文总量的16．98％。BrS 研究主题词主要集中于基因、心电图表现、室性心律失常、猝死及 ICD 植入等。结论BrS 相关研究目前主要集中在欧美发达国家，我国的研究应在整体质量和数量上进一步提高。

Bibliometric analysis of literatures on Brugada syndrome included by Medline

Objective To summarize and analyze the distribution characteristics of research lit-eratures on Brugada syndrome (BrS).Methods With the retrieving tool of GoPubMed,we re-trieved BrS-related literatures included by Medline from January 1 ,1 992 to December 31 ,201 5 and made bibliometric analysis on the distribution characteristics of published year,area,journal,re-search theme,etc.Results A total of 2 220 papers were retrieved.The number of research litera-tures gradually increased after 1 998 and reached relative peak value in recent three years.The lead-ing countries in BrS literature quantity were the United States(386 papers,1 7.39%),Japan(353 papers,1 5.90%)and France (1 33 papers,5.99%)successively,and China ranked the 1 1 th(53 papers,2.39%).The top three literature-output cities were Amsterdam in Holland(80 papers), Tokyo in Japan(70 papers)and Utica in America(58 papers).Beijing was the leading literature-output city in China,ranking the 36th(1 3 papers)in the world,and it was followed by Nanjing and Guangzhou which were tied for the 43rd place(7 papers)globally.The first three journals were Heart Rhythm(1 44 articles),Journal of Cardiovascular Electrophysiology(1 43 articles)and Pacing and Clinical Electrophysiology(90 articles),which published 1 6.98% of all the BrS-related arti-cles.Themes of BrS research mainly focused on genes,electrocardiographic manifestations,ventric-ular arrhythmias,sudden death,ICD implantation and so on.Conclusion BrS,related studies mainly concentrate in developed countries.Chinese researchers should strive to improve the overall quality and quantity of BrS research.