Strict management of a pregnant patient with giant coronary artery aneurysm due to Kawasaki disease |
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Authors: | Kosuke Taniguchi Hiroshi Ono Anna Sato Satoko Kinomoto Naomi Tagawa Nagayoshi Umehara Hitoshi Kato Haruhiko Sago |
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Affiliation: | 1. Center of Maternal‐Fetal, Neonatal and Reproductive Medicine;2. Division of Cardiology, National Center for Child Health and Development, Setagaya, Tokyo, Japan |
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Abstract: | Coronary artery aneurysms (CAA) may occur in Kawasaki disease (KD). Patients with giant CAA (diameter >8 mm), in particular, have higher risk of myocardial infarction. Previous reports have demonstrated the necessity of anticoagulation therapy in such cases. The management of patients with KD complicated by giant CAA later in life, however, remains controversial. Here, we describe the strict management in the case of a 28‐year‐old pregnant Japanese woman with KD with giant CAA (diameter, 11 mm). Instead of warfarin, the patient was given low‐dose aspirin and i.v. unfractionated heparin during pregnancy to prevent thrombosis in the giant CAA. At 38 weeks of gestation, she had spontaneous delivery of a healthy baby. No thrombotic or bleeding complications were observed. The strict anticoagulation therapy resulted in successful pregnancy and delivery without any adverse events. |
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Keywords: | coronary aneurysm Kawasaki disease low‐dose aspirin pregnancy unfractionated heparin |
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