BK virus nephropathy in a pediatric patient after hematopoietic stem cell transplantation |
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| Authors: | E. Gutovskaya A. Mitrofanova D. Balashov A. Maschan |
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| Affiliation: | 1. Department of Hematopoietic Stem Cell Transplantation, the Rogachev Federal Research Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russia;2. Department of Pathology, the Rogachev Federal Research Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russia;3. Deputy Director for Science, the Rogachev Federal Research Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russia |
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| Abstract: | ![]()
We report the case of a seven‐yr‐old Caucasian girl who presented with progressive deterioration of renal function 13 months after HSCT for myelodysplastic syndrome. BK virus nephropathy was suspected and confirmed. After reduction of immunosuppression and treatment with IVIG, leflunomide, ciprofloxacin, and cidofovir, clearance of BK virus from blood was achieved, and further progression or renal failure was prevented. We believe that BK virus nephropathy should be considered in cases of renal function deterioration in all immunocompromised patients. |
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| Keywords: | BK virus nephropathy BK polyomavirus hematopoietic stem cell transplantation renal insufficiency |
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