绵阳市男男性行为人群HIV/梅毒新发感染及影响因素分析

目的了解绵阳市男男性行为者(MSM)艾滋病病毒(HIV)/梅毒新发感染情况及其影响因素。方法 2009年采用应答推动抽样法(RDS)在绵阳招募调查符合条件的HIV阴性的MSM建立随访研究队列,1年后进行相关行为学随访调查和HIV/梅毒等血清学检测。结果在155例随访者中,平均年龄(28.92±7.80)岁,HIV确证阳转9例,新发感染率为5.2/100人年;梅毒阳转13例,新发感染率为7.6/100人年;丙肝无阳转。单因素分析,年龄、婚姻状况、户籍、艾滋病知识知晓、寻找性伴场所、梅毒感染(现症感染)、近6个月性伴最小年龄和近1年接受性病检查/治疗、HIV咨询/检测与HIV新发感染相关,年龄、户籍、首次性行为对象和近6个月以偶然性伴为主与梅毒新发感染相关(P<0.01或P≤0.05)。多因素分析寻找性伴场所(OR=12.346)、梅毒现症感染(OR=6.699)、近1年接受HIV咨询检测(OR=17.123)为HIV新发感染的独立影响因素,户籍(OR=16.860)、首次性行为对象(OR=5.378)、近6个月以偶然性伴为主(OR=7.3531)为梅毒新发感染独立影响因素。结论绵阳市MSM人群HIV/梅毒新发感染率较高,防治形势严峻,应加大防治力度。

Analysis on the New HIV/Syphilis Infections of MSM in Mianyang and the Influencing Factors

Objective To find out the current situation and influencing factors of the new HIV/syphilis infections among MSM(men who have sex with men) in Mianyang.Methods HIV/syphilis negative MSM were recruited anonymously adopted by the Respondent-driven Sampling(RDS),and their were given the HIV/syphilis test by blood one year later.Results One hundred and fifty-five follow-up persons were surveyed,of whom the average age was(28.92±7.80),9 of them were HIV positive,newly infection rate was 5.2/100 per person/year;13 of them were syphilis positive,newly infection rate was 7.6/100 per person/year;no hepatitis C infection.Single factor analysis:the difference of the infection rate of HIV/syphilis(accumulative infection) of people with different incomes,ages,occupations,marriage situation,having different places to find sex partners,having a number of sex partners in the last 6 months,having one night stand with most of the sex partners in the last 6 months,age of having the first sex action,having maximum age of the sex partners in the last 6 months were related to HIV/syphilis infection(P<0.01 or P≤0.05).Multi factors analysis:places to find sex partners(OR=12.346),present state infection of syphilis(OR=6.699),having HIV consultation or test in the last year(OR=17.123) are the independent influencing factors of new HIV infection.Census register(OR=16.860),first sex activity(OR=5.378),having one night stand in the last 6 months(OR=7.3531) were the independent influencing factors of new syphilis infection.Conclusion The infection rate of HIV/syphilis of MSM in Mianyang is relative high;the pointed references should therefore be reinforced.