| 沙利度胺治疗结节性痒疹 |
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| 引用本文： | 张瑛,郑捷. 沙利度胺治疗结节性痒疹[J]. 中国皮肤性病学杂志, 2012, 26(9): 847-849 |
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| 作者姓名： | 张瑛 郑捷 |
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| 作者单位： | 上海交通大学医学院附属瑞金医院皮肤科,上海,200025 |
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| 摘 要： | 结节性痒疹是以瘙痒性结节为临床特征的慢性炎症性皮肤病,病因不明,目前尚无理想的治疗方法。本病由于症状明显、病程长,严重影响患者健康和生活质量;并使临床医师感到困惑。目前已有较多报道显示小剂量沙利度胺(≤100mg/d)对顽固性结节性痒疹的治疗具有较高的有效性和安全性。治疗过程中,需密切观察沙利度胺的不良反应,尤其是外周神经炎,一旦发生需立即停用。
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| 关 键 词： | 结节性痒疹 治疗 沙利度胺 外周神经炎 |
Thalidomide Treatment of Prurigo Nodularis |
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| ZHANG Ying , ZHENG Jie. Thalidomide Treatment of Prurigo Nodularis[J]. The Chinese Journal of Dermatovenereology, 2012, 26(9): 847-849 |
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| Authors: | ZHANG Ying ZHENG Jie |
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| Affiliation: | (Ruijin Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200025,China) |
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| Abstract: | Prurigo nodularis is a chronic inflammatory cutaneous disease characterized with papulonodular pruriginous eruptions. Till now,the etiology has been unknown so that it has been a refractory disease yet. Prurigo nodularis is harmful severely to the health and affected severely the life quality. Physicians are always puzzled with the treatment of it. Low-dose thalidomide therapy (≤100mg)should be regarded as a safe and effective treatment to patients with recalcitrant idiopathic prurigo nodularis. Side-effects of thalidomide should be observed closely,especially peripheral neuropathy. When it occurs,the thalidomide should be ceased. |
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| Keywords: | Prurigo nodularis Therapy Thalidomaide Peripheral neuropathy |
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